One of the most talked about alternative treatments is skin cancer and CBD. There are many people who claim they have cured all three of the major forms of skin cancer: basal cell carcinoma (BCC), squamous cell carcinoma (SCC), and melanoma. Even if it was just a “wild experiment,” there would be no reason to believe that CBD or any other non-psychoactive cannabinoids could hurt you so many people give it a try just based on what they hear through the grapevine or read on the internet. However, there is also a growing body of scientific evidence that backs up the anecdotal claims that CBD and other cannabinoids can indeed cure skin cancer.
Here is a brief discussion of some of those studies:
The regulation of gene expression during the differentiation of skin cells (changes in skin cells as they grow, cells taking on specialized forms and functions, and proliferation of cells) is important in how skin cells remain normal or develop into cancerous cells. This is thought to be controlled by the endocannabinoid system which can signal to the genes inside skin cells when to turn on and off. Cannabinoids produced by the body normally play a role in how these genes are regulated, but where there is cancerous growth, this system does not work properly.
It has long been thought that the cannabinoids found in the oil extracted from the medical cultivars of cannabis plants, like the ones we sell, can work just like the natural cannabinoids produced in a healthy body to regulate the genes responsible for skin differentiation. These cannabis cannabinoids include CBD, CBG, and CBV. A study published October 2013 in the British Journal of Pharmacology showed that CBD and CBV can combine with the CB1 or CB2 receptors of the endocannabinoid system and control gene regulation, thus controlling the differentiation of skin cells. CBG did not have this effect. Furthermore, CBD and CBV were able to stop and reverse skin cells that had started to become cancerous.
A study in October 2013 in the European Journal of Pharmacology showed that anandamide (AEA), a naturally occurring cannabinoid in the body, can stop the growth of malignant melanoma cells in vitro. AEA is known to interact with receptors on the endocannabinoid system just as CBD does when CBD oil is taken. It was also found that the concentration of AEA used could change the results. A study published August 2013 in the Journal of Pharmacy and Pharmacology showed a 90 percent decrease in the skin cancers in mice using synthetic cannabinoids (JWH-018, -210, and -122).
Although the above studies are fairly recent, another pertinent study goes all the way back to 2003 and was published in the Journal of Clinical Investigation. The researchers found that by activating the cannabinoid receptors, CB1 and CB2, with cannibanoids, they were able to induce apoptotic death of the tumorous cells! With the introduction of cannibinoids, the cancer tumors could not vascularize, and therefore, could not get any blood to the new growth areas of the tumor. Subsequently, the tumors died off.
While more research is needed on skin cancer and CBD, the research that has already been done is very promising. This may be why so many people have reported excellent results with treating skin cancers with CBD oil.
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