Cannabinoids are compounds found in the cannabis plant, and are known for their anti-inflammatory and antibacterial properties. Cannabidiol’s (CBD) popularity in the cannabinoid industry has grown significantly in the past few years. These days, it’s not too uncommon to have a friend who’s tried it, or to see it in a local store. With all eyes on CBD, some brands have taken the initiative to manufacture products centering another cannabinoid: CBG.
What is CBG? Cannabigerol (CBG), is one of the many cannabinoids found in the cannabis plant. CBG is also known as the ‘mother of cannabinoids’ because it is the antecedent from which all other cannabinoids are made. CBG-A, the acidic form of CBG, breaks down when heated. This makes not only CBG, but also CBD and tetrahydrocannabinol (THC), as well as cannabichromene (CBC). (1)
Similar to CBD, CBG is a non-psychoactive cannabinoid that attaches to the receptors in the endocannabinoid system. CBG is mostly abundant in low-THC and high–CBD strains. It is believed to have direct interaction with the brain’s CB1 and CB2 receptors; these are key components in regulating physiological and cognitive processes.
So, which one is better? While more research is readily available on CBD, there is enough on both cannabinoids to get a sense of how they interact with the body respectively.
CBG effects on the body:
CBG may work against inflammation, pain, and nausea. It could also potentially help to slow the spread of cancerous cells. There’s research to show that CBG may reduce intraocular eye pressure from glaucoma. High CBG strains may also have the potential to help with conditions such as inflammatory bowel disease and Crohn’s disease. (2)
CBD effects on the body:
Similar to CBG, CBD has properties that may help with anxiety, insomnia, stress, and pain. Studies show that CBD may help to reduce severe pain by interacting with endocannabinoid receptors and neurotransmitters. (3)
Which one offers better benefits: CBD vs CBG
When it comes to sleep, CBD has properties that can help with relaxation and calmness. CBD can also be infused with melatonin, to enhance sleep naturally.
There isn’t as much research available on CBG and its effects on sleep. However, due to the entourage effect, CBG could possibly enhance CBD’s potential properties, which can help to promote a good night’s rest.
According to a consumer reports study, the top reason why people used CBD oil was for stress. Research has shown that CBD may counter stress responses by reducing blood pressure and dilating blood vessels.
Similar to CBD, CBG attaches to receptors that indirectly affect the brain’s chemistry when there are stress-related issues. CBG, when combined with CBD, may help to increase CBD’s individual properties with stress because of the entourage effect.
Common pain and soreness were revealed as the second main reason as to why people chose CBD oil, according to the same consumer study. CBD molecules sends messages to CB2 receptors that can help to alleviate minor pains.
CBG research has shown that the cannabinoid is also useful with minor aches and pains, and more specifically with swelling in the skin. (4)
CBG also serves as an adversary to TRPM8 receptors, which have been known to cause tumors. Through this TRPM8 channel, CBG may have a positive effect on colon cancer in humans, according to preclinical research. (5)
Sourcing plays a role in the cost of CBD and CBG. According to ACS Library, a7 Hemp Benchmarks’ report showed that “up to 25K pounds of CBD Biomass sold for around $4.02 per percentage of CBD per pound (wholesale) in June 2019.” The cost has since decreased by 67% overall, leaving the selling price at $1.31 as of January 2020.
Another Hemp Benchmarks’ report showed that the price of CBG biomass varies, but typically sells for roughly $22.42 per percentage of CBG per pound (wholesale), equaling around $175–325/pound overall. (6)
Consumers can expect to pay an overall higher price for CBG products, due to their high-demand and low supply. CBG’s extraction also requires more effort.
Both CBD and CBG offer benefits of their own. They both allegedly help to provide relief from common issues such as inflammation, anxiety, and stress. However, when combined, they enhance each other, and may provide unique benefits through the entourage effect.
Isolating CBD from hemp is more common than isolating CBG. This makes CBD easier to research due to its availability. The lack of studies on CBG make it harder to confirm all of its potential benefits—however, regardless of this lack of research compared to CBD, it is gaining momentum in the cannabinoid industry. Studies have shown that CBG can help with more issues than CBD such as stopping bacterial growth, the proliferation of cancer cells, and eye pressure from glaucoma. (7)
When it comes down to determining which cannabinoid is better for you, it‘s best to identify your personal needs. Make sure to take caution, until more research is available on all of the possible benefits and side-effects of CBG.
Disclaimer: This article is based on our independent research. While our team does everything in their power to provide accurate and current information from credible state-run websites and resources, we are not lawyers or legal experts. As such, none of the following information should be interpreted as legal advice. Content on these pages is provided for informational purposes only and those with legal concerns should consult experts within their state, such as the FDA.
1) “What is the Difference Between CBD and CBG?”, Source: https://www.labroots.com/trending/cannabis-sciences/18030/difference-cbd-cbg
2) “Meet CBG, the New Cannabinoid on the Block”, Source: https://www.healthline.com/health/cbg-oil
3) “7 Benefits and Uses of CBD Oil (Plus Side Effects)”, Source: https://www.healthline.com/nutrition/cbd-oil-benefits
4) “CBG vs. CBD: Differences, Benefits, Uses & More”, Source: https://www.cbdmd.com/blog/post/cbg-vs-cbd-differences-benefits-uses-more
5) “Colon carcinogenesis is inhibited by the TRPM8 antagonist cannabigerol, a Cannabis-derived non-psychotropic cannabinoid”, Source: https://pubmed.ncbi.nlm.nih.gov/25269802/
6) “HEMP & CBD MARKET VALUE: JANUARY 2020 PRICE TRENDS FOR CRUDE, FLOWER BIOMASS, ISOLATE”, Source: https://acslabcannabis.com/blog/education/hemp-cbd-market-value-price-trends-for-crude-flower-biomass-isolate/
7) “CBG vs CBD: What Are the Differences?” Source: https://www.analyticalcannabis.com/articles/cbg-vs-cbd-what-are-the-differences-312232