An increasing number of Americans have started exploring the use of CBD for its
potential health benefits, as more news and commentary emerges about this trending
substance. CBD has become a buzzword in the natural health arena, especially as an
alternative natural method for potentially helping with pain management. Consequently,
CBD has become an increasingly discussed topic in theories and opinions around
neuropathy, and ways to manage the debilitating symptoms it can cause. If you have
experienced neuropathic pain, you may understand the reasons why many continue to
seek and explore new and alternative methods for relief and management of symptoms.
What is CBD?
CBD, or cannabidiol, is an active organic compound and the second most prevalent
ingredient of the cannabis plant. It is one of 113 known cannabinoids in the plant,
accounting for up to 40% of the plant’s extract. (1)
Cannabinoids produce effects in the body’s endocannabinoid system by stimulating
receptors so that the body produces its own cannabinoids. The receptors in the
endocannabinoid system are responsible for monitoring pain, inflammation, movement,
mood, emotions, and other vital physiological and neurological functions. According to
some clinical studies, CBD oil may possibly be used to help minimize the symptoms of
numerous health conditions, including chronic pain and physical disorders. (4)
Curious as to whether CBD could help with your neuropathy symptoms? Read on to
better understand this emerging alternative trend and learn more about the positive
potential effects of CBD for neuropathic pain, in addition to pharmaceutical medicine.
What is Peripheral Neuropathy?
Neuropathy refers to nerve damage or dysfunction outside of the brain, which causes
varied degrees of chronic pain, weakness or numbness. It is estimated to effect 25-30% of
Americans of all ages, although older individuals are considered at higher risk of being
Risk factors that increase the likelihood of peripheral neuropathy include diabetes,
cancer, metabolic syndrome, thyroid disorders, alcoholism and others. The name
peripheral neuropathy is ascribed as it is not an isolated medical condition but rather, a
description of health problems that cause peripheral nerve damage. (2)
The level of pain related to neuropathy depends largely on how badly the nerve is
damaged, but any amount of neuropathic pain can be an impediment to one’s quality of
life and ability to feel comfortable.
Nerve pain can be caused by a number of things, such as:
- Repeated stress
- Metabolic and endocrine disorders
- Autoimmune diseases
- Traumatic injury
- Cancer Tumors
Common symptoms of neuropathy are:
- A severe and persistent pain that starts and stops intermittently. This may affect you for any duration of time, from a several days to months or even years.
- Pain in the lower back, buttocks or upper thighs.
- Pain that is relieved by changing your posture or lying down.
- Pain that intensifies when you bend, twist or contort your body in ways that cause additional stress.
- Pain that gets worse when you’re in a seated or resting position, but may subsideor feel less painful when you move around again. (2)
This kind of pain can be difficult to manage indefinitely, and may lead to physical and
emotional stress. In an ideal world, a long-term and effective solution for chronic pain
would exist. But, while CBD is certainly not a cure, it may possess some healing qualities
that benefit patients afflicted by painful neuropathic symptoms.
CBD Oil for Neuropathy: How it May Work
The CB1 and CB2 receptors function in the endocannabinoid system and are responsible
for transmitting pain signals to the brain. The effect of CBD is thought to activate the
CB1 receptor, which then potentially responds by decreasing nerve pain.
In its most pure form, CBD is naturally derived from the cannabis or hemp plant, along
with other naturally occurring cannabinoids. Authentic and pure CBD should contain no
more than 0.3% of THC—the other chemical compound in the plant that can impair
mental and neurological functions or cause mind-altering psychoactive effects, such as
euphoria and disorientation. Some studies and research into how CBD, minus the
presence of THC, can impact brain function hypothesize that the substance is supposedly
sedating and relaxing, but not intoxicating. (3)
CBD has become a widely-used ingredient in treatments intended for alleviating pain,
inflammation and other common conditions suffered by humans and mammals. There are
reportedly an increasing number of patients that utilize CBD regularly to help manage
their chronic pain symptoms. Some consumers claim that CBD also assists in reducing
inflammation that exacerbates their physical pain.
The CBD Market and Legal Status
CBD’s growing reputation for potentially providing many health benefits with low risks,
has coincided with its legalization in many parts of the United States. However, it is still
not a regulated substance and its legal status differs between local regions. This has
driven demand and supply of a wide range of products, available in different forms and
strengths from various manufacturers. If you suffer from chronic pain, consult with your
personal physician before using CBD products, or any other alternative medicinal
treatment that is not federally regulated or recognized as an official medication.
How to take CBD Oil for Neuropathic Benefits
There are many different methods by which CBD can be administered. One of the most
popular and well-known ways is with CBD oil, which is essentially a processed and
diluted form of CBD extract. There are varied opinions on what constitutes the best CBD
products available on the market.
One of the most publicly endorsed advantages of CBD is its versatility, and how many
believe it may help a wide variety of conditions and problematic symptoms. While CBD
is not considered a cure by any medical standards, and conclusive evidence of its
purported benefits is still needed, its trending reputation has outpaced conclusive
scientific research. Despite the traditionally taboo reputation of cannabis, cannabidiol has
become increasingly more mainstream and universally acknowledged as a natural
Some of most commonly used CBD products and methods of use include:
One way of ingesting CBD oil is to inhale CBD-infused vapor liquid. Vaping devices
known as vape pens or mods are designed to be used with cartridges or pods containing
You can administer CBD topically with lotions, serums, creams, and numerous other
skincare products designed for topical use. CBD patches are another variation of topical
Edibles have become a trending method for ingesting CBD. There are CBD-infused
chocolates, candies, cakes, capsules, pills, tinctures, and even beverages. CBD gummies
are one of the most popular and the most sold CBD edibles currently available on the
When taking CBD oil in any form, it’s highly advisable that you do some research on
dosage levels and recommendations. Dosages are recommended based on the health
profile of the designated consumer, and the medical reasons for using CBD. In some
clinical research studies, daily dosages used on patients ranged from 100 – 800 mg. (5)
Potency and purity ranges from full-spectrum CBD to broad-spectrum, and it’s important
to know the difference in product labels. It’s also important to acknowledge that certain
methods of application can have different effects on the body. For example, when
administered orally, the CBD oil is more quickly absorbed into the blood stream, which
may accelerate any effects it has in the body.
Side Effects of CBD Oil
According to the World Health Organization, “…In humans, CBD exhibits no effects
indicative of any abuse or dependence potential…To date, there is no evidence of public
health related problems associated with the use of pure CBD.” (6)
Although CBD oil maintains a good safety profile and is generally considered to be well
tolerated by humans, there are some common side effects that consumers may be subject
to, and should be aware of. (4)
Potential adverse side effects could include:
- Mood changes
- Change in appetite
- Dry mouth
Some people experience one or a few of these known symptoms, while others have no
adverse side effects. From a scientific standpoint, every human body is unique in its
chemical composition. Just as with any medication or natural supplement, an average
consumer’s reactions to CBD may vary, and there’s no way of knowing for certain how
your own body will respond to this naturally-derived chemical—whether positively,
negatively or neutrally.
With time and regular or increased usage, your tolerance to CBD will build, and this may
impact how your body starts to adjust to having it in its system. You may experience
fewer aftereffects than you initially had, or they may disappear altogether over time. In
the event of a significant reaction to CBD products, you should immediately stop using
the product in question and see a physician to have your health checked and get some
professional medical advice on treatment options.
Considering CBD Oil for Neuropathy
One of the most appealing and plausibly advantageous aspects of CBD is that it is
natural, not chemically synthesized. Unlike opioids and other pharmaceutical drugs used
for acute and chronic pain, CBD is not known to be habit-forming or addictive. With
heightened global concerns about addiction to chemical substances, natural alternatives
are largely met with curiosity and positive feedback from consumers that suffer from the
effects of neuropathy.
CBD has generated high interest and excitement for its potential benefits—especially for
pain management—but should be also be regarded with some caution about the possible
placebo effect. The number of news and social media reports praising and advocating for
CBD are arguably high, but many aren’t backed by concrete scientific facts and evidence.
So, ensure you seek information on CBD from reputable scientific sources. With that
being said, if you chronically suffer from neuropathic pain and are curious about using
natural alternatives for potential relief, CBD oil may be a good option for you to explore.
If you’re interested in learning more about the different types of CBD products, please
explore our website or contact us.
1. "How Many Different Cannabinoids Are There?”, Source:
2. “Neuropathy (Peripheral Neuropathy)”, Source:
3. “Everything you need to know about CBD oil”, Source:
4. “A Cross-Sectional Study of Cannabidiol Users”, Source:
5. “What is the correct dosage of CBD?”, Source:
6. “Cannabidiol (CBD) – what we know and what we don’t”, Source: